Important Publications

1. Sreerama, L. and Sladek, N. E. Aldehyde dehydrogenases: Measurement of activities and protein levels, In: E. Hodgson, Current Protocols in Toxicology, (2005; Invited review).
2. Ong, S.-S. Reberg, A. Chan, W.-H. and Sreerama, L . Detoxification of chloroacetaldehyde by aldehyde dehydrogenases present in human kidney, Enzymology and Molecular Biology of Carbonyl Metabolism-12, 2005 (In Press).
3. Lovold, A., Smith, N., Kuyomba, U Reberg, A., Gregory, D. and Sreerama, L., Role of Human Aldehyde Dehydrogenases in Ethylene Glycol Ether Metabolism: Oxidation of 2-Butoxyethanal and 2-Phenoxyethanal, Enzymology and Molecular Biology of Carbonyl Metabolism-12, 2005 (In Press)
4. Murrary, D., A. Scott, L. Sreerama, N. E. Sladek and B. S. Andersson. Characterization of altered gene expression in a cyclophosphamide-resistant human myeloid leukemia cell line, KBM-7/B5- 180 3, Cancer Chemother. Pharmacol., 2004 (Submitted).
5. Lakshmipathy, U., Tabah, A., Sreerama, L., Sladek, N. E. and C. R. Campbell, Generation and characterization of a MCF-7 cell line resistant to flavopiridol with unique pattern of cross-resistance to drugs, Cancer Chemother. Pharmacol., 2005 (in press).
6. Sreerama, L., and Hardin. G. G., Effect of freezing and thawing on the concentration of ethanol in urine samples stored in leak-proof plastic bottles. J. Forensic. Sci., 48:672-676, 2003.
7. Sladek, N. E., Kollander, R. Sreerama L., and Kiang, D. T., Cellular levels of aldehyde dehydrogenases (ALDH1A1 & ALDH3A1) as predictors of Therapeutic responses to cyclophosphamide-based chemotherapy of breast cancer: A retrospective study. J. Cancer Chemother. Pharmacol., 49:309-321, 2002.
8. Sreerama, L. and Sladek, N. E. Primary breast tumor levels of suspected molecular determinants of cellular sensitivity to cyclophosphamide, ifosfamide, and certain other anticancer agents as predictors of paired metastatic tumor levels of these determinants: Rational individualization of cancer chemotherapeutic regimens. Cancer Chemother Pharmacol., 47:255-262, 2001
9. Sreerama, L. and Sladek, N. E. Three different stable human breast adenocarcinoma sublines that overexpress ALDH3A1 and certain other enzymes as consequence of constitutively upregulated gene transcription mediated by transactivated EpREs (electrophile responsive elements) present in the 5'-upstream regions of these genes. Chemico-Biological Interactions, 130-132:247-260, 2001.
10. Steinkellner, H., Hietsch, G., Sreerama, L., Haidinger, G., Gsur, A., Kundi ,M. and Knasmuller, S. Induction of glutathione S-transferases in humans by vegetable diets. In: Dietary Anticarcinogens and Antimutagens, Eds. I. T. Johnson and G. R. Fenwick, pp. 193-198. Royal Society of Chemistry Science Network Press, 2000.